Research Highlights / Integrated Computational Engineering

Overview

Several faculty at IIT Hyderabad (from Civil, Chemical, Material Science and Metallurgy, and Mechanical engineering) work on various length scales and multi-physics problems. This work includes simulations using density functional theory, molecular dynamics, discrete dislocation dynamics, crystal plasticity, phase-field, fracture mechanics, fatigue, plasticity, damage mechanics, micromechanics of defects, non-local methods, meshless methods, and conventional FEM connecting one scale to another. The rich diversity in the problems being studied at IITH along with the strong publications portfolio makes us an ideal destination for solutions in the Integrated Computational Engineering area.

Team

Faculty Department Representative Project
Kishalay Mitra Chemical Engineering Opt imization of Mechanical Properties of Hot Rolled Steel using Evolutionary as well as Classical Approaches
Shourya Dutta Gupta Materials Science and Metallurgical Engineering Spinodal Decomposition in Cu-Ag Alloy Thin Films- A Route to Tunable Plasmonics
Niranjan S. Ghaisas Mechanical and Aerospace Engineering
Viswanath Chintapenta Mechanical and Aerospace Engineering Bio-mechanical Simulations of Resuscitation
Anand Mohan Chemical Engineering Math ematical Modelling of Autowaves Phase Transforms and Surface Chemical Reactions in Blood Coagulation
Ashish Misra BioTechnology
Raja Banerjee Mechanical and Aerospace Engineering Uncertainty Estimation in External Flow CFD Simulations
Rajakumara Eerappa BioTechnology Mechanistic studies on high mobility group nucleosome ( HMGN 1) Bindingprote in complexex involved in DNA Repair.
Thenmalarchelvi R BioTechnology Structural Insights into RNA Duplexes Comprising Trinucleotide Repeat Extensions and their Implications in Alternative Splicing Misregulation by MBNL1

Publications

Girdhar, Amandeep, Vidhya Bharathi, Vikas Ramyagya Tiwari, Suman Abhishek, Waghela Deeksha, Usha Saraswat Mahawar, Gembali Raju et al. “Computational insights into mechanism of AIM4-mediated inhibition of aggregation of TDP-43 protein implicated in ALS and evidence for in vitro inhibition of liquid-liquid phase separation (LLPS) of TDP-432C-A315T by AIM4.” International Journal of Biological Macromolecules (2020).

Ghaisas, Niranjan S., Aditya S. Ghate, and Sanjiva K. Lele. “Effect of tip spacing, thrust coefficient and turbine spacing in multi-rotor wind turbines and farms.” Wind Energy Science 5, no. 1 (2020): 51-72.

Ameenuddin, Mohammed, Mohan Anand, and Mehrdad Massoudi. “Effects of shear-dependent viscosity and hematocrit on blood flow.” Applied Mathematics and Computation 356 (2019): 299-311.

Matta, Seshadri, Naresh Reddy Kolanu, Viswanath Chinthapenta, C. M. Manjunatha, and M. Ramji. “Progressive damage analysis of adhesively bonded patch repaired carbon fibre–reinforced polymer specimen under compression involving cohesive zone model.” International Journal of Damage Mechanics (2019): 1056789519832062.

Patro, L. Ponoop Prasad, Abhishek Kumar, Narendar Kolimi, and Thenmalarchelvi Rathinavelan. “3D-NuS: a web server for automated modeling and visualization of non-canonical 3-dimensional nucleic acid structures.” Journal of molecular biology 429, no. 16 (2017): 2438-2448.

Misra, Ashish, and Michael R. Green. “Fluorescence Reporter-Based Genome-Wide RNA Interference Screening to Identify Alternative Splicing Regulators.” In Eukaryotic Transcriptional and Post-Transcriptional Gene Expression Regulation, pp. 1-12. Humana Press, New York, NY, 2017.