K-PAM: Klebsiella species serotype predictor and surface antigens modeler

... An In silico Diagnostic Tool

Lipopolysaccharide is an immunodominant antigen. In Enterobacteriaceae family, LPS comprises three parts (i) hydrophobic lipid A (ii) core oligosaccharide linked to lipid A and (iii) O antigen. The core polysaccharide is usually divided into inner core and outer core. The inner core is highly conserverd in Enterobactericeae family. Nine O antigens have been reported in Klebsiella spp. The structures are built by CHARMM LPS modeler (LPS Modeler).



Click on the following links to get the 3D structure information of the O antigens

O1        O2a        O2c        O2aeh        O2afg        O3        O4        O5        O7        O8        O12


Lipid A and core structure from Klebsiella are given below


Structural details of O-antigens from Klebsiella

Antigen Name       : O1


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Antigen Name       : O2a


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Antigen Name       : O2c


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Antigen Name       : O2aeh


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Antigen Name       : O2afg


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Antigen Name       : O3


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Antigen Name       : O4


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Antigen Name       : O5


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Antigen Name       : O7


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Antigen Name       : O8


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Antigen Name       : O12


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Schematic representation:

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